by Mohammad Saleem, Faiza Naseer, Sohail Ahmad, Attiya Nazish, Fiza Raza Bukhari, Atta Ur Rehman, Imran Mahmood Khan, Samra Sadiq and Fatima Javed
Original Research
The hepatoprotective activity of Conyza bonariensis ethanol extract was studied against paracetamol induced hepatotoxicity in mice. The results showed that an extract of C.B (250 mg/kg and 500 mg/kg) produced (p<0.05) decline in paracetamol induced liver marker enzymes and total bilirubin, but its 750 mg/kg showed remarkable decline in ALT, AST, ALP and TB levels, compared to the reference levels of silymarin and results were supported by histopathology of liver section. So, it is concluded that 750 mg/kg is highly potent dose of ethanol extract of Conyza bonariensis and this potential may be due to the presence of the active constituent: qurecetin and chromatogram by HPLC confirmed its presence.why do men cheat on their girlfriends
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American Journal of Medical and Biological Research. 2014, 2(6), 124-127. DOI: 10.12691/ajmbr-2-6-2
Pub. Date: January 04, 2015
17419 Views5298 Downloads36 Likes
by Sabitha Kandi, Sudhakar T, C Ramadevi, B Venugopal, Rajkumar, Md Rafi and K V Ramana
Review Article
Preeclampsia is an idiopathic multisystem disorder specific to pregnancy and development of hypertension and proteinuria, increased vascular resistance and endothelial dysfunction in the mother , altered placental perfusion and restricted fetal growth. The vasospasm leads to destruction of RBCs release iron thus, there is elevated serum iron levels in preeclamptic women. The excess iron released from destruction of RBCs can react with free radicals produced from cell membrane (as it is rich in polyunsaturated fatty acids) and circulating lipoproteins initiates lipid peroxidation both in placenta and vasculature. This is one of the significant etiologic factors in the endothelial cell damage of preeclampsia. the raised serum iron levels in turn alters the iron related parameters like total iron binding capacity(TIBC), serum ferritin, transferrin, percent saturation.best spyware for android cell phones
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American Journal of Medical and Biological Research. 2014, 2(6), 121-123. DOI: 10.12691/ajmbr-2-6-1
Pub. Date: December 29, 2014
14845 Views4831 Downloads41 Likes2 Citations