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American Journal of Medical and Biological Research. 2014, 2(4), 87-90
DOI: 10.12691/AJMBR-2-4-1
Original Research

The Set Point of Intact Parathyroid Hormone-Ionized Calcium Curve during the Progression of Secondary Hyperparathyroidism among Patients Undergoing Haemodialysis

T Sudhakar1, Sabitha Kandi2, B venugopal2, K. Bhagwan Reddy3 and K. V. Ramana3,

1Department of Biochemistry, HOD lab in-charge, Apollo Reach Hospital, Karimnagar, Andhra Pradesh

2Department of Biochemistry, Chalmeda Anadrao Institute of Medical Sciences, Karimnagar

3Department of Biochemistry, Prathima Institute of Medical Sciences, Karimnagar

Pub. Date: August 19, 2014
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T Sudhakar, Sabitha Kandi, B venugopal, K. Bhagwan Reddy and K. V. Ramana. The Set Point of Intact Parathyroid Hormone-Ionized Calcium Curve during the Progression of Secondary Hyperparathyroidism among Patients Undergoing Haemodialysis. American Journal of Medical and Biological Research. 2014; 2(4):87-90. doi: 10.12691/AJMBR-2-4-1

Abstract

The parathyroid gland secretes parathyroid hormone (PTH) which is a key element in the regulation of serum calcium. The PTH elevates serum calcium activities by regulating its action on the bones, kidneys and small intestine. The set point of PTH secretion defines the sensitivity of the parathyroid glands to calcium concentration. Secondary hyperparathyroidism (SHPT) is a common complication of end stage renal disease (ESRD). Ionized calcium is physiologically active form of calcium status of the body and is used for accurately monitoring calcium status in renal diseases. The present study states that the ionized calcium is the set point of secondary hyperparathyroidism undergoing haemodialysis and the range of set point lies between 2.3 – 4.8 mg/dl (0.57 – 1.2 mmol/L). The status of iPTH, set point are frequently monitored in subtotal hyperparathyroidectomy where imaging studies are not beneficial (anatomically situated on postero-lateral surface of thyroid gland) to know the appearance of parathyroid gland.

Keywords

set point, ionized calcium, Secondary hyperparathyroidism (SHPT), haemodialysis

Copyright

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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